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Ethyl ferulate

CAS No. 4046-02-0

Ethyl ferulate( BBR 3222 | NSC 14879 )

Catalog No. M14386 CAS No. 4046-02-0

Ethyl ferulate is extracted from angelica, Chuan Xiong.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ethyl ferulate
  • Note
    Research use only, not for human use.
  • Brief Description
    Ethyl ferulate is extracted from angelica, Chuan Xiong.
  • Description
    Ethyl ferulate is extracted from angelica, Chuan Xiong.
  • In Vitro
    Western Blot Analysis Cell Line:RPE cells (induced by 150 μM CoCl2 for 12 h)Concentration:40 μM Incubation Time:2 h Result:Increased Nrf-2 expression and nuclear translocation.Decreased Keap-1 expression, Aand increased HO-1 and NQO-1 expression.Reduced hypoxia-induced HIF-1α and VEGFA expression.
  • In Vivo
    Animal Model:LPS (0.5 mg/kg)-induced acute lung injury mice model Dosage:15 and 30 mg/kg Administration:i.p., twice a day for 5 days Result:Reduced leukocyte infiltration.Reduced MPO activity, mRNA levels and secretion of TNF-α and IL-6.
  • Synonyms
    BBR 3222 | NSC 14879
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    4046-02-0
  • Formula Weight
    222.24
  • Molecular Formula
    C12H14O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    CCOC(=O)/C=C/C1=CC(=C(C=C1)O)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.nazaré AC, et al. Molecules. 2014 Jun 17;19(6):8124-39.
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